Stem Cells

Stem cells are multipotent cells capable of differentiating into a spread of cell types, including muscle cells. it had been originally hypothesized that stem cells implanted into the myocardial milieu would differentiate into cardiomyocytes to exchange those lost during the myocardial infarct . Animal studies demonstrated that somatic cell transplantation was safe and potentially efficacious. Bone-marrow-derived stem cells, endothelial progenitor cells and stem cells isolated from fat are the foremost widely used for implantation into the injured myocardium. The encouraging results of the preclinical studies triggered variety of clinical trials. the first clinical trials established the feasibility of somatic cell therapy to repair the injured myocardium.

 

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