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Dean Nizetic


Dean Nizetic

Nanyang Technological University, Singapore

Biography

Dean Nizetic has become one of the leading researchers and opinion-makers in molecular research into Down Syndrome (DS), in particular its relation to stem cell pathology, ageing and cancer. He has recently generated isogenic induced Pluripotent Stem Cells (iPSC) by re-programming the skin fibroblasts from an adult individual with mosaic DS and then cloning separately the genetically identical T21 and euploid (D21) iPSC lines. He is currently leading the Ipsc-cellular modeling stream within the LonDownS consortium. From February 2014, he is a Professor of Molecular Medicine at Lee Kong Chian School of Medicine, Singapore.

 

Abstract

Abstract : Cellular modeling of trisomy 21 as an approach to understand Alzheimer’s disease