Zhi-Cheng Xiao
Professor
Head, Neurodegeneration and Regeneration Group Monash Biomedicine Discovery Institute. USA
United States of America
Biography
Dr. Zhi-cheng Xiao is currently a professor in Monash University, who has both extensive academia and industrial experiences. He was awarded a Doctor of Natural Science Degree from Swiss Federal Institute of Technology, Zurich, in 1996. He was also trained in Harbin Medical University, University of Science and Technology of China and Beijing Medical University as both a medical and Ph.D student. He was a postdoctoral fellow of University of California, Irvine, University of Southern California, University of Rochester in USA, McGill University in Canada, and University Hamburg in Germany. He joined Singapore General Hospital in 2000 as a principal investigator; Institute of Molecular and Cell Biology, Singapore in 2004 and Hong Kong University in 2008 as an Associate Professor. He joined GSK in 2009 as a Director of Innovative Research and joined Monash University in 2011 as a full professor. He established IRP Health, a premier Bio-Tech company, targeting the problem of antibiotic resistance, in 2014.
Research Interest
A novel nodal β-amyloid hypothesis: validating the involvement of sodium channel Nav1.6 in the pathogeneses of Alzheimer’s disease. Identification of upstream molecule that triggers APP/JNK3 singnalling pathway after optic nerve injury and confirmation of JNK3 plays a key role in the apoptosis of retinal ganglin. Can downregulation of adult neurogenesis be involved in Alzheimer’s disease (AD)? An exploration of how TAG1/APP signalling promotes AD pathogenesis through JNK3 regulated by AICD-dependent transcriptional activity